ABSTRACT
Introducción: La velocidad de la onda de pulso y la rigidez arterial se considera estándar de oro para evaluar daño a órganos diana que haya surgido subclinicamente. La disfunción endotelial es directamente proporcional al desarrollo de la aterosclerosis preclínica. Estos marcadores sustitutos mencionados anteriormente son relativamente más altos en pacientes con hipertensión no controlada o resistente. El objetivo fue evaluar si la rigidez arterial y la velocidad de la onda del pulso también son marcadores sustitutos del desarrollo de la aterosclerosis preclínica en pacientes con hipertensión resistente. Métodos y materiales: Se incluyeron en el estudio un total de 160 pacientes con hipertensión resistente de Croacia e India. La presión arterial central y otros valores clínicos se evaluaron utilizando un dispositivo no invasivo. Resultados: Las estadísticas del grupo se hicieron con perspectiva de género, los valores de la presión arterial sistólica (PA-S), la presión arterial diastólica (PA-D), la presión arterial media (PAM), la presión central sistólica (PC-S) ,la presión central diastólica ( PC-D), la presión de pulso central (cPP) y la velocidad de la onda de pulso (VOP) han sido descritas. Los valores de PA-S en hombres / mujeres fueron 147.26 ±22.12/ 144.10 ± 21.29; los valores de PA-D en hombres/mujeres fueron 94.98 ± 13.36 / 88.57 ± 12.25 respectivamente. Conclusiones: con los resultados obtenidos se puede concluir que la rigidez arterial es un marcador independiente que es directamente proporcional a la disfunción endotelial y al desarrollo de aterosclerosis preclínica.
Introduction: Pulse wave velocity and arterial stiffness are considered a gold standard for evaluating target organ damage that has arisen subclinically. Endothelial dysfunction is directly proportional to the development of preclinical atherosclerosis. These surrogate markers mentioned above are relatively higher in patients with uncontrolled or resistant hypertension. The objective was to assess whether arterial stiffness and pulse wave velocity are also surrogate markers for the development of preclinical atherosclerosis in patients with resistant hypertension. Methods and materials: A total of 160 patients with resistant hypertension from Croatia and India were included in the study. Central blood pressure and other clinical values were evaluated using a non-invasive device. Results: The statistics of the group were made with gender perspective, the values of the systolic blood pressure (PA-S), the diastolic blood pressure (PA-D), the mean arterial pressure (MAP), the central systolic pressure (PC-S), central diastolic pressure (PC-D), central pulse pressure (cPP) and pulse wave velocity (VOP) have been described.The PA-S values in men / women were 147.26 ± 22.12 / 144.10 ± 21.29; PA-D values in men / women were 94.98 ± 13.36/88.57 ± 12.25 respectively. Conclusions: with the results obtained, it can be concluded that arterial stiffness is an independent marker that is directly proportional to endothelial dysfunction and the development of preclinical atherosclerosis.
Subject(s)
Cardiovascular Diseases , Atherosclerosis , Vascular Stiffness , Arterial PressureABSTRACT
Snakebite is a common medical emergency in India. Unusual complications may occur after viper bite. Bilateral parotid enlargement after viper bite is a rare entity. An 18-year old gentleman presented to our hospital with history of viper bite. On examination he had cellulitis of right lower limb. He developed swelling of both the parotid glands 12 h after admission. He developed coagulopathy, acute renal failure and died within 48 h of hospital admission. Development of parotid swelling after snake bite is associated with poor prognosis. This case is found worth reporting as it is an unusual complication having prognostic value.
Subject(s)
Adolescent , Animals , Humans , Male , Acute Kidney Injury , Blood Coagulation Disorders , Fatal Outcome , India , Parotid Diseases , Pathology , Parotid Gland , Pathology , Prognosis , Russell's Viper , Snake BitesABSTRACT
Fetal malnutrition [FM] implies soft tissue wasting at birth with significant postnatal consequences and morbidity, and is identified by clinical assessment [CAN score] and anthropometry. No previous studies have been done to study all these parameters and evolve a screening method. The aim of this study was identifying the incidence of FM using CAN score and compare the nutritional assessment with anthropometry and evolve a screening tool for rapid assessment of FM. Prospective study in Government district maternity hospital. 300 term newborns were assessed by CAN score and anthropometry recorded. The newborns were classified as per weight for age. Ponderal index [PI], Body mass index [BMI] and midarm circumference/head circumference ratio [MAC/HC] calculated and compared to CAN Score for accuracy in identifying FM. Incidence of FM was 24%. Newborns identified malnourished by PI, BMI, MAC/HC were evaluated by CAN score and significant number of them [31/78 in PI, 60/121 in BMI, 51/81 in MAC/HC] were found well nourished. Similarly those recognized as normal by PI, BMI, MAC/HC were malnourished by CAN score [25/222 in PI, 11/179 in BMI, 42/219 in MAC/HC] with statistical significance[0.0001]. BMI had the highest sensitivity and 11 neonates with normal BMI had low CAN score ann 9 of them had normal PI also making a combination of BMI and PI a good indicator of normal nutrition. FM is best identified by CAN Score. BMI is the best screening tool for malnutrition and when coupled with PI will identify most normally nourished newborns